View source for UDP-N-acetylgalactosamine-4-sulfate sulfotransferase

{{enzyme
| Name = 4-chlorobenzoyl-CoA dehalogenase
| EC_number = 3.8.1.7
| CAS_number = 141583-18-8
| IUBMB_EC_number = 3/8/1/7
| GO_code = 0018787
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''4-chlorobenzoyl-CoA dehalogenase''' ({{EC number|3.8.1.7}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:4-chlorobenzoyl-CoA + H<sub>2</sub>O <math>\rightleftharpoons</math> 4-hydroxybenzoyl CoA + chloride

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[4-chlorobenzoyl-CoA]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[4-hydroxybenzoyl CoA]] and [[chloride]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on halide bonds in carbon-halide compounds.  The systematic name of this enzyme class is '''4-chlorobenzoyl CoA chlorohydrolase'''. This enzyme participates in [[2,4-dichlorobenzoate degradation]].  

==References==
{{reflist|1}}
* {{cite journal | author = Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D | date = 1992 | title = Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3 | journal = Biochemistry.  | volume = 31 | pages = 5605&ndash;10  | pmid = 1610806 | doi = 10.1021/bi00139a025 | issue = 24 }}
* {{cite journal | author = Crooks GP, Copley SD | date = 1994 | title = Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1 | journal = Biochemistry.  | volume = 33 | pages = 11645&ndash;9  | pmid = 7918379 | doi = 10.1021/bi00204a028 | issue = 38 }}

{{hydrolase-stub}}

[[Category:EC 3.8.1]]
[[Category:Enzymes of unknown structure]]