https://en.formulasearchengine.com/w/api.php?action=feedcontributions&feedformat=atom&user=144.82.115.4formulasearchengine - User contributions [en]2026-08-07T07:13:14ZUser contributionsMediaWiki 1.47.0-wmf.7https://en.formulasearchengine.com/w/index.php?title=Cluster_state&diff=19474Cluster state2013-10-23T18:20:07Z<p>144.82.115.4: I forget the cretinous mathtypesetting on wp sometimes...</p>
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<div>{{enzyme<br />
| Name = homocysteine desulfhydrase<br />
| EC_number = 4.4.1.2<br />
| CAS_number = 9024-41-3<br />
| IUBMB_EC_number = 4/4/1/2<br />
| GO_code = 0047982<br />
| image = <br />
| width = <br />
| caption = <br />
}}<br />
In [[enzymology]], a '''homocysteine desulfhydrase''' ({{EC number|4.4.1.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]<br />
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:L-homocysteine + H<sub>2</sub>O <math>\rightleftharpoons</math> hydrogen sulfide + NH<sub>3</sub> + 2-oxobutanoate<br />
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[L-homocysteine]] and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[hydrogen sulfide]], [[ammonia|NH<sub>3</sub>]], and [[2-oxobutanoate]].<br />
<br />
This enzyme belongs to the family of [[lyase]]s, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is '''L-homocysteine hydrogen-sulfide-lyase (deaminating 2-oxobutanoate-forming)'''. Other names in common use include '''homocysteine desulfurase, L-homocysteine hydrogen-sulfide-lyase''', and '''(deaminating)'''. This enzyme participates in [[nitrogen metabolism]] and [[sulfur metabolism]]. It employs one [[cofactor (biochemistry)|cofactor]], [[pyridoxal phosphate]]. <br />
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==References==<br />
{{reflist|1}}<br />
* {{cite journal | author = KALLIO RE | date = 1951 | title = Function of pyridoxal phosphate in desulfhydrase systems of Proteus morganii | journal = J. Biol. Chem. | volume = 192 | pages = 371&ndash;7 | pmid = 14917685 | issue = 1 }}<br />
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{{enzyme-stub}}<br />
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[[Category:EC 4.4.1]]<br />
[[Category:Pyridoxal phosphate enzymes]]<br />
[[Category:Enzymes of unknown structure]]</div>144.82.115.4